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Magic™ Membrane Protein Human SDC2 (Syndecan 2) Expressed in NS0 for Antibody Discovery, Partial (19-144aa) (CAT#: MPX0397K)

Datasheet
This product is a 14.8 kDa Human SDC2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SDC2
  • Protein Length
  • Partial (19-144aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 14.8 kDa
  • TMD
  • 1
  • Sequence
  • ESRAELTSDKDMYLDNSSIEEASGVYPIDDDD
    YASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQ
    TKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTE

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SDC2
  • Full Name
  • Syndecan 2
  • Introduction
  • The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
  • Alternative Names
  • SDC2; HSPG; CD362; HSPG1; SYND2; syndecan-2; cell surface-associated heparan sulfate proteoglycan 1; fibroglycan; heparan sulfate proteoglycan 1, cell surface-associated; heparan sulfate proteoglycan core protein; syndecan proteoglycan 2; Syndecan 2

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