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Magic™ Membrane Protein Escherichia coli MAP1LC3B2 (Microtubule associated protein 1 light chain 3 beta 2) for Antibody Discovery (CAT#: MP0673X)

This product is a 16.2 kDa Escherichia coli MAP1LC3B2 membrane protein expressed in Escherichia coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Escherichia coli
  • Target Protein
  • MAP1LC3B2
  • Protein Length
  • Full-length
  • Molecular Weight
  • 16.2 kDa
  • Sequence
  • MGSSHHHHHHSSGLVPRGSHMPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVCASQETFG

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • Escherichia coli expression system
  • Tag
  • Escherichia coli
  • Purification
  • Conventional Chromatography
  • Purity
  • > 95% by SDS-PAGE
  • Buffer
  • 20 mM Tris-HCl buffer, 0.1 M NaCl, pH 8.0 (1 mM DTT, 10% glycerol)

Target

  • Target Protein
  • MAP1LC3B2
  • Full Name
  • Microtubule associated protein 1 light chain 3 beta 2
  • Introduction
  • Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).
  • Alternative Names
  • ATG8G

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